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#1
May 05, 2026, 01:22 AM
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It is the only distinct SGA I have not tried, and I am going to try it. I am currently on Lybalvi, which is Zyprexa+, and the only other regimen that worked for me was Geodon+ low-dose Seroquel, but it didn't eliminate the side effects I had on Zyprexa, so Lybalvi has won as a more elegant monotherapy.
I know Caplyta is for bipolar depression more so than for maintenance against both poles, but has anyone who has a tendency towards mania when unmedicated successfully incorporated Caplyta into their regimen? And how have you been sleeping on it? Has anyone experienced Caplyta triggering hypomania?
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Bipolar I w/psychotic features Last inpatient stay in 2018 Lybalvi 5/10 mg Gabapentin 1200 mg Naltrexone 2 mg Vitamin B-complex (against extrapyramidal side effects) Long-term side effects from medications, some of them discontinued: - Hypothyroidism - Obesity |
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#2
May 05, 2026, 04:28 AM
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I did respond to you on my thread, but my doctor isn't putting me on it because she thinks there is a big risk of it triggering mania for me (who has pretty reliably gotten manic or thrown into rapid cycling from every antidepressant I've ever been on and antipsychotics geared towards depression like Rexulti) and that risk would outweigh any benefit I could get from it.
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Something’s always coming you can hear it in the ground It swells into the air with the rising, rising sound And never comes, but shakes the boards and rattles all the doors What are we waiting for? What are we waiting for? |
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#3
May 05, 2026, 09:11 AM
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It did trigger mania & psychosis in me. I ended up in the psych hospital.
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Bipolar 1, PTSD, anorexia, panic disorder, ADHD quetiapine (Seroquel), Cymbalta, lamotrigine, lithium, guanfacine (Intuiv), pantoprazole, famotidine, iron, magnesium, fish oil, vitamin C, Citracal There's a crack in everything. That is how the light gets in. --Leonard Cohen |
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#4
May 05, 2026, 06:34 PM
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My pdoc doesn't want me on it out of fear that it will cause mania. It caused mania in a few of his patients.
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Lamotrigine: 400 mg Bupropion: 150 mg Risperidone: 4 mg Quetiapine: 100 mg Lithium: 900 mg |
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#5
Yesterday, 11:34 PM
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I haven't tried it yet because the insurance required people authorization.
I scanned reddit posts and many people went manic on it, including engaging in reckless behavior that was out of character for them.
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Bipolar I w/psychotic features Last inpatient stay in 2018 Lybalvi 5/10 mg Gabapentin 1200 mg Naltrexone 2 mg Vitamin B-complex (against extrapyramidal side effects) Long-term side effects from medications, some of them discontinued: - Hypothyroidism - Obesity |
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#6
Today, 05:30 AM
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I wonder if they're going to eventually change it's indications to be for MDD and contraindicated for bipolar. I know the commercials it initially had advertised it for bipolar depression but if a lot of people are reporting going manic and doctors are not prescribing it for mania risk, maybe people with bipolar shouldn't take it (or take it in the way they take antidepressants--alongside a med that actually prevents mania)? Just a thought from someone who speaks out of whatever hole is working most efficiently that day.
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Something’s always coming you can hear it in the ground It swells into the air with the rising, rising sound And never comes, but shakes the boards and rattles all the doors What are we waiting for? What are we waiting for? |
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